Combipres is also known generically as clonidine and chlorthalidone and is commonly used in the treatment of high blood pressure. Combipres is a combination medication. One medication (clonidine) relaxes the blood vessels and allows the heart to pump blood through the body with less resistance as well as slows the rate at which the heart beats. The other medication (chlorthalidone) reduces edema and swelling by increasing the body's salt and water which is lost in the process of urination. Chlorthalidone is a diuretic.
Combipres may affect patients differently and may cause worsening of some medical conditions. It is recommended that the prescribing physician assess a thorough medical evaluation prior to prescribing Combipres. Patients with a medical history which includes liver disease, a previously known allergy to sulfa based drugs, or the current use of an MAO inhibitor can not take Combipres. Patients with a medical history which includes kidney disease, diabetes, gout, heart attack, stroke, heart disease, pancreatitis, high cholesterol, high level of triglycerides in the blood, or a collagen vascular disease like systemic lupus may or may not be able to tolerate Combipres and may require special monitoring while undergoing drug therapy with Combipres, depending on the condition and the severity of the condition.
According to the American Food and Drug Administration, Combipres has been granted a pregnancy risk category B rating, which means that there is no expectation that Combipres will cause harm or birth defects in a developing fetus. However, Combipres does pass through the mother's breast milk and could cause harm to a nursing baby. Women who are pregnant should weigh the risks versus the benefits while women who are nursing should avoid taking Combipres. Combipres has not been approved for the therapeutic use in children