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Asacol prescription: Mesalazine is a derivative of salicylic acid and is thought to be the active component of sulfasalazine (Azulfidine), a combination of a sulfa drug and salicylic acid. Mesalamine works as an antiinflammatory agent in treating ulcerative colitis and Crohn's disease. Its benefit is believed to be due to a topical effect on the inflamed bowel. Following rectal administration of mesalamine (by enema or suppository), only 15% of a dose is absorbed. Following oral administration, 28% of a dose is absorbed. Mesalamine is used for the treatment of mild to moderately severe colitis. The suppositories are limited to use in proctitis, the enemas to distal colitis (colitis involving only the part of the colon close to the rectum) or proctitis.
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Asacol is used in the treatment of Inflammatory Bowel Disease (IBD). IBD is a general term for any condition that involves chronic inflammation of the small intestine and colon walls. Two main types of IBD exist: ulcerative colitis (UC) and Crohn's disease (CD). Both disorders follow a course of exacerbations (flare-ups) and remissions. UC and CD are troublesome and chronic diseases that can have a significant impact on patients' lives.
Mesalazine acts locally by reducing the inflammation in the wall of the small intestine and the colon.
Asacol is used in the:
* Treatment (induction of remission) of mild to moderate active ulcerative colitis
* Maintenance of remission in ulcerative colitis
In a number of countries Asacol is additionally approved for one or both of the following uses:
* Treatment (induction of remission) of mild to moderate active Crohn's ileocolitis
* Maintenance of remission in Crohn's ileocolitis